Hi Rajiv,

Thanks for the questions.

1. The transit studies were requested by physicians or surgeons investigating transit time in children with chronic constipation. Only children with chronic constipation were included in the audit.
2. It is suggested that children with increasingly slower transit times are managed more aggressively as this correlates with a greater disease burden. As such the use of simple oral laxatives alone with a transit time >100 hours is unlikely to be effective. So more intensive combination treatment regimes are required to successfully treat these children. This illustrates that clinicians likely consider the degree of slow transit and also treat the child based upon the wider clinical context in keeping with NICE guidance.
3. We hope this study will help clinicians gain insight into the current clinical management of chronic constipation. With data to illustrate current practice following interpretation of transit study results. The changes to radiology reporting will improve the ease of interpretation of colonic transit study reports and so improve the medical management of constipation.

Kind regards